Chronic Lymphocytic Leukemia - Deuterated Water Study
Direct Measurement of Leukemic Cell Turnover (Synthesis and Removal) in Patients with Chronic Lymphocytic Leukemia Using Deuterated Water (GAC 0004)
Protocol ID
Protocol Description
In patients with leukemia, blood cells, both normal cells and leukemic cells, are produced in the bone marrow to replace cells that have died or been removed. This process of replacement is called cell turnover.
This study will look at the cell turnover of leukemia cells in patients with chronic lymphocytic leukemia using a method to measure the production and destruction rates of cells. This study will also evaluate cell turnover of normal blood cells in healthy individuals (“normal controls”). Normal controls are used in research to study the differences between individuals who have a disease and those who do not.
Eligibility Criteria
Patients with chronic lymphocytic leukemia and healthy volunteers
Primary Investigator(s)
- Nicholas Chiorazzi, MD