Hodgkin Disease Study
AHOD0031 A Phase III Group-Wide Study of Dose-Intensive Response-Based Chemotherapy and Radiation Therapy for Children and Adolescents with Newly Diagnosed Intermediate Risk Hodgkin Disease
Protocol ID
02.10.166T
Protocol Description
The purpose of this study is to learn whether we can modify treatment for Hodgkin disease in a way that reduces therapy for rapid early responders and increases therapy (and hopefully outcome) in slow early responders. In particular, the goals of the study are:
- To find out if more therapy for slow early responders is better than the standard therapy.
- To find out if patients who have an early complete response to chemotherapy can be treated successfully without radiation therapy.
- To find out if certain factors like symptoms, age, sex, and blood test results predict how well a patient will respond to treatment.
- To find out which late effects occur after Hodgkin disease treatment and how often they occur; and
- To collect information on how PET scans provide useful information about which places in the body are affected by Hodgkin Disease in children and teenagers.
Eligibility Criteria
Children and teenagers with Hodgkin disease
Primary Investigator(s)
- Arlene Redner, MD