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Clinical Trials

Children with Newly Diagnosed Brain Tumors - Pilot Study

Dose Intensive Chemotherapy for Children Less Than Ten Years of Age Newly-Diagnosed With Malignant Brain Tumors:  A Pilot Study of Two Alternative Intensive Induction Chemotherapy Regimens, Followed by Consolidation With Myeloablative Chemothera

Protocol ID

03-093T

Protocol Description

The main purpose of this clinical research study is to learn whether intensive chemotherapy for a period of three to five months, followed by a highly intensive single course of drug treatment with a blood stem cell rescue procedure, can improve the cure rates for young children diagnosed with one of the following malignant brain tumors: a medulloblastoma, a primitive neuroectodermal tumor (PNET), an ependymoma, a choroid plexus tumor, an atypical choroid plexus papilloma or an atypical teratoid/rhabdoid tumor (ATT/R).

Secondly, the study will look at the effects of lower dose radiation treatment on normal brain development.

Eligibility Criteria

Children with one of the following malignant brain tumors: a medulloblastoma, a primitive neuroectodermal tumor (PNET), an ependymoma, a choroid plexus tumor, an atypical choroid plexus papilloma or an atypical teratoid/rhabdoid tumor (ATT/R)

Primary Investigator(s)

  • Mark Atlas, MD

Contact Information

Alyssa Quinlan, PA-C
(718) 470-4356
aquinlan1@nshs.edu

Last Update

March 29, 2010
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