Pediatric Serotonin Metabolism Study
Serotonin Metabolism in Children with Functional Gastrointestinal Disorders: The Impact of Persistent Inflammation GAC # 0186
Protocol ID
Protocol Description
The purpose of this study is to look at how the human body uses serotonin (a chemical in the body) and how this use affects the motility (movement) and inflammation of the gastrointestinal tract.
New medications for adults with functional gastrointestinal complaints have been shown to be successful in reducing such symptoms. These medications are used to correct abnormalities in how the body uses serotonin (metabolism).
These abnormalities in serotonin metabolism have not been studied in children. Understanding them in children could lead to more effective therapy for children with functional gastrointestinal disease.
Eligibility Criteria
Children who have been diagnosed with irritable bowel syndrome or inflammatory bowel disease
Primary Investigator(s)
- Jeremiah Levine, MD