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Clinical Trials

Rheumatoid Arthritis - Lovastatin Therapy Study

ARA02: A Double Blind, Placebo Controlled, Phase II, Randomized Study of Lovastatin Therapy in the treatment of mildly active Rheumatoid Arthritis

Protocol ID

07.02.013

Protocol Description

This study will look at the effects of a drug called Lovastatin in the treatment of patients with mildly active rheumatoid arthritis (RA). Lovastatin is one of the “statin” drugs approved by the FDA for the treatment of high cholesterol, but it is currently not approved for treating RA. There is evidence from laboratory studies that Lovastatin may be beneficial in the treatment of mildly active RA. One purpose of this study is to determine if Lovastatin is effective in reducing the inflammation that is seen in patients with mildly active RA. Another purpose is to see if it is safe for treatment of mildly active RA. This study will look at the effects of Lovastatin by comparing subjects with RA who receive the study drug, Lovastatin, to those who do not.

Eligibility Criteria

Patients with mildly active rheumatoid arthritis (RA)

North Shore University Hospital
300 Community Drive
Manhasset, NY 11030
Contact Information: (516) 562-0100

Primary Investigator(s)

  • Cynthia Aranow, MD

Contact Information

Sanita Kandasami
(516) 562-2401
skandasami@nshs.edu

Last Update

March 25, 2010
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