Iron Overload Evaluation Study
Evaluation of Iron Overload in Pediatric Oncology and Hematopoietic Stem Cell Transplant Patients
Protocol ID
Protocol Description
The purpose of this study is to see if pediatric oncology and transplant patients who finished their treatment 1-10 years ago have elevated iron levels in their blood. Based on studies done on thalassemia and transplant patients who regularly received blood transfusions, we know that thalassemia and transplant patients who regularly received blood transfusions suffer from too much iron in their blood, which can result in damage to the heart, liver, and endocrine system. If iron levels are very high, patients may develop heart and liver failure which can cause death. There is currently highly effective treatment for this condition (known as ‘iron overload’) which can prevent or even reverse the damage already done to the body. Therefore it is important to know which patients are at risk for having too much iron in their system.
Eligibility Criteria
Patients who have had the following diagnoses: acute myelogenous leukemia, rhabdomyosarcoma, Ewing sarcoma, osteosarcoma, neuroblastoma, and transplant patients who were diagnosed with a malignancy
Primary Investigator(s)
- Jennifer Eng