How Is CVS Performed?

Before and during the procedure, all patients will have an ultrasound examination. Ultrasound uses sound waves to create a picture of the uterus and developing fetus. Once the age of the fetus has been confirmed, the doctor also uses ultrasound to locate and identify the safest site for the sampling. At this time, the decision is made whether the tissue will be obtained transvaginally or transabdominally. If the tissue is to be obtained transvaginally, you will be asked to lie on your back with your legs in stirrups, like a pelvic exam. The vagina will be held open with a sterile speculum and cleaned with an antiseptic solution. Using ultrasound guidance, the doctor will gently insert a thin plastic catheter through the cervix (opening of the uterus) to reach the chorionic villi. You may feel some light cramping similar to menstrual cramps. No anesthesia will be needed. When the catheter is in the proper location, a small sample of tissue will be removed.

If the procedure is to be done transabdominally, you will be asked to lie on your back. Your abdomen will be cleaned with a sterile antiseptic. Under ultrasound guidance, the doctor will insert a thin needle into your abdomen, through your uterus and guide it into the placental tissue. You will feel a small pinch and some light cramping and pressure as the tissue is removed.

The tissue is examined under a microscope to ensure the amount is adequate and then sent to the lab for analysis.

Results are usually available within 10 to 14 days and will be sent directly to your doctor who will then notify you. In certain situations, a rapid result (FISH) can be obtained within 48 to 72 hours.

After the procedure you should avoid heavy lifting and strenuous activity for about 24 hours. You may have slight spotting or staining for up to a week, especially if you have the transvaginal CVS.

You should notify your doctor if you experience:

  • Flu-like symptoms (body aches, nausea or vomiting)
  • Fever abdominal cramping
  • Pain
  • Severe vaginal bleeding
  • Increased vaginal discharge

Last Update

May 24, 2010
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