Mood Disorders
Genetics of Psychiatric Disorders
(NIMH)
PI: Anil Malhotra, MD
Contact: Pam Derosse (718) 470-8725
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Research program evaluating the DNA of individuals, ages 16 to 65, with schizophrenia and other psychotic disorders.
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Treatment and Outcome of Early Onset Bipolar Disorder
(NIMH)
PI: Vivian Kafantaris, MD
Contact: Alison Berest (718) 470-8362
Treatment study of adjunctive antipsychotic medication in adolescents, ages 12 to 18, experiencing acute mania with aggressive and/or psychotic features.
Comparing Three Electrode Placements to Optimize ect
(NIMH)
PI: Georgios Petrides, MD Chitra Malur, MD
Contact: Christopher Phillips, RN (718) 470-8163
Treatment program comparing the efficacy and safety of three ect techniques in individuals with depression.
Can Donepezil HCL (aricept) ameliorate cognitive deficits associated with ECT?
(Pharmaceutical Company Support)
PI: Raphael Braga, MD
Contact: Christopher Phillips (718) 470-8163
This double-blind placebo-controlled study examines the possible usefulness of donepezil (aricept) to reduce cognitive side-effects associated with ect.
Neurocognitive Endophenotypes in Bipolar Disorder
(NARSAD)
PI and Contact: Kate Burdick, PhD (718) 470-8167
This study collects information about the performance of patients with bipolar disorder on tests of cognition, such as concentration, memory, and thinking. Siblings will be asked to participate in the procedures, as well as participants who are diagnosed with bipolar disorder who will be compared with patients and their siblings.
Effects of Cortisol on Cognition During ECT For Major Depression
(NARSAD)
PI: Chitra Malur, MD
Contact: Christopher Phillips, RN (718) 470-8136
Study looks at relationship of endogenous cortisol in patients with major depressive disorder who are receiving ECT.
Acute Effects of ECT On Melatonin Levels
PI: Georgios Petrides, MD
Contact: Christopher Phillips, RN (718) 470-8163
Examines how ECT affects endogenous melatonin levels.
Continuation ECT vs Pharmacotherapy
PI: Georgios Petrides, MD
Contact: Christopher Phillips, RN (718) 470-8163
Comparing efficacy and safety of ECT with nortriptyline combined with lithium in treating patients with major depressive disorders.
Serotonin Modulation & Function in Geriatric Neuropsychiatry
(NIMH)
PI: Gwenn S. Smith, Ph.D.
Contact: Susan Ray (718) 470-8442
The glucose metabolic response to acute, intravenous citalopram administration will be evaluated in normal aging and in patients with geriatric depression. The glucose metabolic response to chronic treatment with citalopram will also be evaluated in patients with geriatric depression.
Pet Studies of Glucocorticoid Modulation in Psychotic Depression
(NARSAD)
PI: Gwenn S. Smith, Ph.D.
Contact: Susan Ray (718) 470-8442
The goal of this study is to measure the effects of glucocorticoid antagonist treatment on cerebral glucose metabolism and dopamine (d2) receptor binding in patients with psychotic depression.
