Ongoing Research in Gastroenterology
The Division of Gastroenterology has an active research program.
The basic research has included: a) cytokine levels in inflammatory bowel disease b) cytokine and other anti-inflammatory levels in acute pancreatitis c) experimental research on the translocation of bacteria through the gut in patients with pancreatitis especially alcoholic pancreatitis.
The clinical research has included: detailed studies on the long-term prognosis and severity parameters in acute pancreatitis, many aspects of chronic pancreatitis and very significantly the effect of local anesthesia on the ampulla of Vater on the ease of cannulation at ERCP and the prevention of post-ERCP pancreatitis. In addition, a study was completed with an anti-inflammatory cytokine in acute pancreatitis i.e., platelet activating antibody factor which proved not to be effective. Many long-term studies on the effect of proton-pump-inhibitors in the long-term treatment of gastroesophageal reflux and a multi-center Long Island study on the effect of proton-pump inhibitors on preventing cancer and dysplasia in Barrett's esophagus. Currently, the division is doing trials on various interferons in Hepatitis C and Hepatitis B and the effect of fatty liver on inflammatory hepatic disease and its prevention.