Health Discoveries in Testicular Cancer
More genetic links to testicular cancer, study finds
August 12, 2010
Three new genetic risk factors linked to testicular cancer have been identified by British researchers, according to a recent issue of the journal Nature.
A research team at the Institute of Cancer Research in the U.K. reviewed the genetic makeup of nearly 6,000 men and found variants in three genetic regions were significantly more common in those with testicular cancer. To confirm their findings, the researchers analyzed an additional 670 patients with testicular cancer patients and 3,500 healthy men.
The study brings the number of genetic regions associated with this form of cancer to six, based on previous studies that had identified three others. The three genes identified by the British scientists are called TERT, ATF7IP and DMRT1.
Testicular cancer is the most common cancer that develops in men ages 15 to 45 years and has a strong hereditary link. Although highly treatable, many survivors experience fertility problems later.
The Genitourinary Service of the North Shore-LIJ Health System includes a team of oncologists who work with the urologists and radiation therapists to develop treatment plans for patients with malignancies that include testicular cancer, prostate cancer, bladder cancer and renal cell cancer.
A research team at the Institute of Cancer Research in the U.K. reviewed the genetic makeup of nearly 6,000 men and found variants in three genetic regions were significantly more common in those with testicular cancer. To confirm their findings, the researchers analyzed an additional 670 patients with testicular cancer patients and 3,500 healthy men.
The study brings the number of genetic regions associated with this form of cancer to six, based on previous studies that had identified three others. The three genes identified by the British scientists are called TERT, ATF7IP and DMRT1.
Testicular cancer is the most common cancer that develops in men ages 15 to 45 years and has a strong hereditary link. Although highly treatable, many survivors experience fertility problems later.
The Genitourinary Service of the North Shore-LIJ Health System includes a team of oncologists who work with the urologists and radiation therapists to develop treatment plans for patients with malignancies that include testicular cancer, prostate cancer, bladder cancer and renal cell cancer.