Gout is characterized by inflamed, painful joints due to the formation of crystal deposits at the joints. Also known as "the disease of kings and the king of diseases," gout affects more men than women and is often associated with obesity, hypertension (high blood pressure), hyperlipidemia (high levels of lipids in the blood), and diabetes.
Like gout, pseudogout is a condition involves the formation of crystals in the joints, but in pseudogout, the crystals are formed from a salt instead of uric acid.
Gout is caused by monosodium urate crystal deposits in the joints, due to an excess of uric acid in the body. The excess of uric acid may be caused by an increase in production by the body, under-elimination of the uric acid by the kidneys, or increased intake of certain foods that metabolize into uric acid in the body. Foods that are high in purines (the component of the food that metabolizes into uric acid) include certain meats, seafood, dried beans, and dried peas.
Alcoholic beverages may also increase levels of uric acid in the body. Gout attacks may be triggered by any/all of the following:
- Consumption of large quantities of alcohol
- Consumption of large quantities of protein-rich foods
- Emotional stress
- Minor surgery
Gout is characterized by sudden, recurrent attacks that often occur without warning. Severe, chronic gout may lead to deformity. The following are the most common symptoms of gout. However each individual may experience symptoms differently. Symptoms may include:
- Severe, sudden pain in one or more joints (most often the joint in the big toe)
- Swollen joint(s)
- Red or purplish, tight, shiny skin over joint
- Warmth in joint area
- General feeling of illness
- Rapid heartbeat
- Hard lumps of urate crystal deposits under the skin (called tophi)